Hey, you know what I was thinking? Only one PC will probably be able to live in a town because of the whole mayor angle in the gameplay. BUT because of ability to save files on an SD card now, there's the possibility of multiple (but large) game files and a new ability to travel between them. I feel like it'd be a bit of a moneygrab if Nintendo didn't include that.
I doubt they’ll get rid of the four-player scenario, since it’s been in every game.